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Portrait: Daphne Haas-Kogan

Daphne Adele Haas-Kogan

Professional Focus Dr. Haas-Kogan is a Board Certified Radiology Radiation Oncologist- Pediatrics. Dr. Haas-Kogan is a Professor of Radiation Oncology, Harvard Medical School.
She has an active laboratory-based research program that investigates novel therapeutic agents for adult and childhood brain tumors, as well as pediatric malignancies. Haas-Kogan is the principle investigator for several clinical trials, including investigator-initiated studies and cooperative group trials run by the Children’s Oncology Group NCI and the Pacific-Pediatric Neuro-Oncology Consortium. A widely published author, she has also received accolades for excellence in teaching and exceptional care delivery.
Honors & Awards 1985 Joseph L. Barrett Award for Teaching, Harvard University
1986 Phi Beta Kappa, Harvard University
1986 Thomas T. Hoopes Prize awarded to Senior Honors Thesis
1986 Summa cum laude awarded to Senior Honors Thesis
1991 Alpha Omega Alpha, University of California, San Francisco
1995 ASTRO Basic Scientist Research Award
1995 Junior Scientist Travel Award, 10th International Congress of Radiation Research
1995 American Cancer Society Clinical Oncology Fellowship
1997 Radiological Society of North America Scholar Award
1998 UCSF Dean representative to Association of American Medical Colleges Professional Development Seminar for Junior Women Faculty, Santa Fe, New Mexico.
1999 Pfizer Scholars Grant for New Faculty.
1999 First place: CAP competition, General Clinical Research Center National Meeting; Arlington, VA.
1999 UCSF-Mount Zion Clinical Investigator Award.
2000 American Society of Clinical Oncology Career Development Award.
2002 Henry J. Kaiser Award for Excellence in Teaching, UCSF School of Medicine.
2002 UCSF Nominee, Assoc of American Medical Colleges (AAMC) Humanism in Medicine Award.
2003 Nominated for Teaching Award, UCSF School of Medicine.
2004 Nominee: Henry J. Kaiser Award for Excellence in Teaching, UCSF School of Medicine.
2005 Selected one of Best San Francisco Doctors for San Francisco Magazine, January 2005.
2006 Alpha Omega Alpha, nominated by Medical Student Class of 2007 for AOA membership in the alumni category at the University of California, San Francisco.
2007-8 Best Doctors in America
2008-9 Best Doctors in America
2009-10 Mentor: Howard Hughes Medical Institute Research Training Fellowship for Medical Students.
2009-10 Best Doctors in America
2014 Regional Top Doctor, Castle Connolly
Research & Publications Selected Publications [100+]:

Clinical outcome and prognostic factors for central neurocytoma: twenty year institutional experience.
Imber, B. S.,Braunstein, S. E.,Wu, F. Y.,Nabavizadeh, N.,Boehling, N.,Weinberg, V. K.,Tihan, T.,Barnes, M.,Mueller, S.,Butowski, N. A.,Clarke, J. L.,Chang, S.... J. Neurooncol. - 2015 Oct 24

Medical Student Perspectives on a Multi-institutional Clerkship Curriculum: A Report From the Radiation Oncology Education Collaborative Study Group.
Ye JC, Mohindra P, Spektor A, Krishnan MS, Chmura SJ, Howard AR, Viswanathan AN, MacDonald SM, Thaker NG, Das P, Mancini BR, Higgins SA, Braunstein S, Haas-Kogan D,... Int J Radiat Oncol Biol Phys - 2015 Jun 1

Quality improvement of International Classification of Diseases, 9th revision, diagnosis coding in radiation oncology: Single-institution prospective study at University of California, San Francisco.
Chen, C. P.,Braunstein, S.,Mourad, M.,Hsu, I. C.,Haas-Kogan, D.,Roach, M.,Fogh, S. E. Pract Radiat Oncol - 2014 Nov 22

Standardization and Quality Assurance of Radiation Therapy Volumes for Adults With High-Grade Gliomas.
Fogh, S.,Wahl, M.,Anwar, M.,Haas-Kogan, D.,Clarke, J. L.,Sneed, P. K. Semin Radiat Oncol - 2014 Sep 16
Pure germinomas of the central nervous system: treatment strategies and outcomes.
Schoenfeld, A.,Haas-Kogan, D. A.,Molinaro, A.,Banerjee, A.,Nicolaides, T.,Tihan, T.,Bollen, A. W.,Gupta, N.,Mueller, S. J. Neurooncol. - 2014 Sep 06

In Reply to Bull et al.
Laprie, A.,LaMarre, A. K.,Haas-Kogan, D. A. Int. J. Radiat. Oncol. Biol. Phys. - 2014 May 20

Likelihood of Bone Recurrence in Prior Sites of Metastasis in Patients With High-Risk Neuroblastoma.
Polishchuk, A. L.,Li, R.,Hill-Kayser, C.,Little, A.,Hawkins, R. A.,Hamilton, J.,Lau, M.,Tran, H. C.,Strahlendorf, C.,Lemons, R. S.,Weinberg, V.,Matthay, K. K.,DuBois,... Int. J. Radiat. Oncol. Biol. Phys. - 2014 May 29

Targeting Wee1 for the treatment of pediatric high-grade gliomas.
Mueller, S.,Hashizume, R.,Yang, X.,Kolkowitz, I.,Olow, A. K.,Phillips, J.,Smirnov, I.,Tom, M. W.,Prados, M. D.,James, C. D.,Berger, M. S.,Gupta, N.,Haas-Kogan, D. A. Neuro-oncology - 2013 Dec 07

Hyperfractionation: fractious or not?
Laprie, A.,LaMarre, A. K.,Haas-Kogan, D. A. Int. J. Radiat. Oncol. Biol. Phys. - 2014 Jan 15

Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure (ABC2) low-grade glioma research workshop.
Huse JT, Wallace M, Aldape KD, Berger MS, Bettegowda C, Brat DJ, Cahill DP, Cloughesy T, Haas-Kogan DA, Marra M, Miller CR, Nelson SJ, Salama SR, Soffietti R, Wen PY,... Neuro Oncol - 2014 Jan

Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial.
Kreissman, S. G.,Seeger, R. C.,Matthay, K. K.,London, W. B.,Sposto, R.,Grupp, S. A.,Haas-Kogan, D. A.,Laquaglia, M. P.,Yu, A. L.,Diller, L.,Buxton, A.,Park, J.... Lancet Oncol. - 2013 Sep

Feasibility, safety, and indications for surgical biopsy of intrinsic brainstem tumors in children.
Cage, T. A.,Samagh, S. P.,Mueller, S.,Nicolaides, T.,Haas-Kogan, D.,Prados, M.,Banerjee, A.,Auguste, K. I.,Gupta, N. Childs Nerv Syst - 2013 Aug

Risk of First and Recurrent Stroke in Childhood Cancer Survivors Treated With Cranial and Cervical Radiation Therapy.
Mueller, S.,Sear, K.,Hills, N. K.,Chettout, N.,Afghani, S.,Gastelum, E.,Haas-Kogan, D.,Fullerton, H. J. Int. J. Radiat. Oncol. Biol. Phys. - 2013 Jul 15

Poly (ADP-Ribose) Polymerase Inhibitor MK-4827 together with Radiation as a Novel Therapy for Metastatic Neuroblastoma.
Mueller, S.,Bhargava, S.,Molinaro, A. M.,Yang, X.,Kolkowitz, I.,Olow, A.,Wehmeijer, N.,Orbach, S.,Chen, J.,Matthay, K. K.,Haas-Kogan, D. A. Anticancer Res. - 2013 Mar

PDGFRA Amplification is Common in Pediatric and Adult High-Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma.
Phillips, J. J.,Aranda, D.,Ellison, D. W.,Judkins, A. R.,Croul, S. E.,Brat, D. J.,Ligon, K. L.,Horbinski, C.,Venneti, S.,Zadeh, G.,Santi, M.,Zhou, S.,Appin, C.... Brain Pathol. - 2013 Sep

Molecular targets and mechanisms of radiosensitization using DNA damage response pathways.
Raleigh, D. R.,Haas-Kogan, D. A. Future Oncol - 2013 Feb

Genotype-dependent cooperation of ionizing radiation with BRAF inhibition in BRAF V600E-mutated carcinomas.
Dasgupta, T.,Haas-Kogan, D. A.,Yang, X.,Olow, A.,Yang, D. X.,Gragg, A.,Orloff, L. A.,Yom, S. S. Invest New Drugs - 2013 Oct

Tumor Dosimetry Using (124)Im-iodobenzylguanidine MicroPET/CT for (131)Im-iodobenzylguanidine Treatment of Neuroblastoma in a Murine Xenograft Model.
Seo, Y., Gustafson, W. C., Dannoon, S. F., Nekritz, E. A., Lee, C. L., Murphy, S. T., Vanbrocklin, H. F., Hernandez-Pampaloni, M., Haas-Kogan, D. A., Weiss, W. A.,... Mol Imaging Biol - 2012 Dec

Hepatocellular carcinoma: natural history, current management, and emerging tools.
Tinkle, C. L., Haas-Kogan, D. Biologics - 2012

High-grade gliomas in children.
Cage, T. A., Mueller, S., Haas-Kogan, D., Gupta, N. Neurosurg Clin N Am - 2012 Jul

PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome.
Mueller, S., Phillips, J., Onar-Thomas, A., Romero, E., Zheng, S., Wiencke, J. K., McBride, S. M., Cowdrey, C., Prados, M. D., Weiss, W. A., Berger, M. S., Gupta, N.,... Neuro Oncol - 2012 Sep

The superiority of conservative resection and adjuvant radiation for craniopharyngiomas.
Schoenfeld, A., Pekmezci, M., Barnes, M. J., Tihan, T., Gupta, N., Lamborn, K. R., Banerjee, A., Mueller, S., Chang, S., Berger, M. S., Haas-Kogan, D. J Neurooncol - 2012 May

Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.
Venkatesh, H.S., Chaumeil, M.M., Ward, C.S., Haas-Kogan, D.A., James, C.D., Ronen, S.M. Neuro Oncol - 2012 Mar
Pediatric Brain Tumors
Pediatric cancer
Medulloblastoma (Brain Tumor)
Glioma (Brain Tumor)
central nervous system tumors
Brain Cancer (Brain Tumor)
Cancer of the Brain (Brain Cancer)
Neurofibromatosis Type 1 (NF1)
Neurofibromatosis Type 2 (NF2)
Wilms Tumor
Ewing Sarcoma (Bone Cancer)
Cancer of the Sympathetic Nervous System (Neuroblastoma)
Ependymoma (Brain Tumor)
intracranial germ cell tumor
Hodgkins Disease
Lymphoma, Hodgkins (Hodgkins Disease)
Craniopharyngioma (Adult Brain Tumors)
Computed Tomography Scan CT
Computed Tomography CT or CAT Scan of the Brain
Magnetic Resonance Imaging MRI Scan
Radiation Therapy
University of California, San Francisco School of Medicine
Medical School
University of California, San Francisco, Radiation Oncology, 1997
California Pacific Medical Center - Pacific Campus Internship, Internal Medicine, 1994
University of California San Francisco, Diller Family Comprehensive Cancer Center, 1992
Board Certifications
American Board of Radiology
Radiation Oncology*
Other Certifications
Radiation Oncology
Hospital Affiliation
Boston Children’s Hospital
Brigham and Women’s Hospital
Dana-Farber Cancer Institute
Place of Work
Professor of Radiation Oncology, Harvard Medical School | Academic | Current
Chair of the Department of Radiation Oncology, Dana-Farber Cancer Institute | Hospital Based | Current
Chair of the Department of Radiation Oncology, Brigham and Women’s Hospital | Hospital Based | Current
Chair of the Department of Radiation Oncology, Boston Children’s Hospital | Hospital Based | Current